Factors Influencing Recombinant Protein Secretion Efficiency in Gram-Positive Bacteria: Signal Peptide and Beyond
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چکیده
منابع مشابه
Protein secretion and surface display in Gram-positive bacteria
The cell wall peptidoglycan of Gram-positive bacteria functions as a surface organelle for the transport and assembly of proteins that interact with the environment, in particular, the tissues of an infected host. Signal peptide-bearing precursor proteins are secreted across the plasma membrane of Gram-positive bacteria. Some precursors carry C-terminal sorting signals with unique sequence moti...
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Bacteria are frequently exposed to a range of different circumstances in which the activation of adaptive mechanisms is essential for cell maintenance and survival. The modulation of such activity is intricately driven through gene regulation, involving diverse events at the transcriptional, translational, and posttranslational levels. Thus, transcription initiation could be considered the majo...
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ژورنال
عنوان ژورنال: Frontiers in Bioengineering and Biotechnology
سال: 2019
ISSN: 2296-4185
DOI: 10.3389/fbioe.2019.00139